WebFrank J D Crease was born circa 1890, at birth place, to William Crease and Lotty Sarah Foster Crease (born Smith). William was born circa 1858, in North Curry, Somerset, England. Lotty was born circa 1864, in Islington, London, England. Frank had 6 siblings: Alice Crease, William P L Crease and 4 other siblings. WebJun 25, 2024 · Coronary artery disease is a global challenge for healthcare systems. Early diagnosis is a key issue to improve quality of life and reduce morbidity and mortality. Diagonal earlobe crease, a wrinkle extending obliquely across the earlobe, was linked by many authors to various atherosclerotic diseases. This systematic review aimed at …
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WebBackground: The diagonal ear lobe crease (ELC) has been suggested as a simple marker of vascular disease in the general population but there are few data from diabetic patients despite their increased risk of angiopathy. Aim: To determine whether the ELC is a clinically useful sign of coronary artery disease (CAD) or retinopathy in type 2 diabetes. WebNov 24, 2024 · Frank’s sign (FS) was described in 1973 as an auricular marker for cardiovascular disease presenting as a crease of the auricular lobule. Since its first clinical description, there have been multiple studies underlining the role of FS in a myriad of conditions, such as atherosclerosis, hypertension, cerebrovascular disease, peripheral … ovid smith
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WebJul 25, 2024 · Frank’s sign is a diagonal crease of the ear lobe, supposedly related to cardiac pathology, and has strongly been associated with coronary artery … WebNov 2, 2011 · Frank suggested that the presence of “a prominent crease in a lobule portion of the auricle” may be indicative of small vessel pathology, possibly explaining the correlation with CAD.[1] Shoenfield and colleagues performed histological examination of earlobe creases and found substantial thickening of the arteriolar walls relative to ... WebJun 30, 2012 · 1. Frank S, et al. Aural sign of coronary artery disease. N Engl J Med 1973;289:327-328. 2. Elliott WJ. Ear lobe crease and coronary artery disease. 1000 patients and review of the literature. Am J Med 1983;75:1024-1032. 3. Evrengul H, et al. Bilateral diagonal ear lobe crease and coronary artery disease: A significant association. ovid strawberry festival 2022