WebDetection Reagent: Human Oncostatin M/OSM Biotinylated Antibody (Catalog # BAF295) Standard: Recombinant Human Oncostatin M (OSM) Protein (Catalog # 295-OM) Neutralization. Measured by its ability to neutralize Oncostatin M/OSM-induced proliferation in the TF‑1 human erythroleukemic cell line. Kitamura, T. et al. (1989) J. Cell Physiol. … WebOncostatin M, also known as OSM, is a protein that in humans is encoded by the OSM gene.. OSM is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it is proving important in liver development, …
Oncostatin M Polyclonal Antibody (PA5-47002) - Thermo Fisher Scientific
WebObjectives: The cytokine oncostatin M (OSM) is implicated in the pathology of systemic sclerosis (SSc). Inhibiting OSM signalling using GSK2330811 (an anti-OSM monoclonal antibody) in patients with SSc has the potential to slow or stop the disease process. WebThe invention provides an isolated antibody, or antigen-binding portion thereof that specifically binds to canine or feline Oncostatin M receptor Beta (OSMR-β) or both, wherein the antibody antagonizes IL-31-mediated signaling or OSM-mediated signaling or both in a canine and/or feline cell. # - hindi fb unlock website
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WebOncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. Web12. apr 2024. · The macrophage oncostatin M (OSM) regulatory pathway was specifically turned on by ischemia. ... In addition, OSM neutralizing antibody significantly reduced OSM expression in macrophages and OSM receptor expression in ischemic tissues (fig. S8, C and D). Compared with the anti–immunoglobulin G (IgG) isotype control group, ... Web03. feb 2024. · Oncostatin M induction of monocyte chemoattractant protein 1 is inhibited by anti-oncostatin M receptor beta monoclonal antibody KPL-716. Acta Derm Venereol. 2024; 100 adv00197 View in Article home liner loan