WebFeb 1, 2024 · Model iCW773 was applied coupled with flux balance analysis and algorithm OptForceMUST for hyaluronic acid biosynthesis to predict genetic interventions in C. … WebJun 30, 2024 · Overproduction of l-proline in WT using OptForceMUST by iCW773 and ModelCg 2. Browse. Search. Explore more content. 13068_2024_856_MOESM8_ESM. xlsx …
MOESM7 of A new genome-scale metabolic model of …
WebIn microbial cultivations for hyaluronic acid (HA) production, oxygen can be a limiting substrate due to its poor solubility in aqueous medium and the substantial increase in culture viscosity at relatively low HA titers. Shear stress due to the high agitation and aeration rates required to overcome oxygen limitation may reduce the quality (i.e., … WebFurthermore, genetic interventions for overproducing L-lysine, 1,2-propanediol and isobutanol simulated using OptForceMUST were in accordance with reported experimental results, indicating the practicability of iCW773 for the design of metabolic networks to overproduce desired products. great gatsby location map
Biosystem design of Corynebacterium glutamicum for …
WebEngineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid Cheng, Fangyu; Yu, Huimin; Stephanopoulos, Gregory download BookSC ... WebOverwhelmed by administrative inefficiencies and expanding legal constraints, our team set out to build a solution that would help companies do it right. Over 20 years later, more … WebFurthermore, genetic interventions for overproducing L-lysine, 1,2-propanediol and isobutanol simulated using OptForceMUST were in accordance with reported exptl. results, indicating the practicability of iCW773 for the design of metabolic networks to overproduce desired products. In vivo genetic modifications of iCW773- predicted targets ... great gatsby literary article