WebTHBS4 is a member of subgroup B of thrombospondins. THBS-4 was first identified in Xenopus laevis embryos as a constituent of the myotome and skeletal muscle (Urry et al., 1998).Inadulthumantissues,thehighestexpressionofTHBS4is found in the heart and skeletal muscles (Lawler et al., 1993). Web12 Feb 2024 · Gastric cancer (GC), a common and lethal cancer in the world, has a high risk of metastasis. Our study was to explore the effects of THBS4 on GC progress and metastasis and the underlying mechanisms. The proliferations of MGC-803 and BGC-823 …
Thrombospondin-4 expression is activated during the stromal
Web1 Oct 2011 · For example, in the developing nervous system, THBS4 was found to represent an attractive substrate for certain neurites and to promote neurite outgrowth in a variety of neuron types. 41 Furthermore, THBS4 has been shown to stimulate the proliferation of … Web6 Sep 2024 · Here, we found HBEGF+ fibroblasts that contributed to RA remission by integrating scRNA-seq datasets and bulk RNA sequencing (bulk RNA-seq) datasets. Method: After identifying cell types by classic marker genes, the integrated dataset was used to … corporate governance anbefalinger
Thbs1 induces lethal cardiac atrophy through PERK-ATF4 …
Web13 Oct 2024 · Thbs4 was shown to promote keratinocyte proliferation and fibroblast migration by activating β-catenin signalling cascade. This indicates that incorporating Thbs4 into novel wound healing therapies can be a promising therapeutic strategy for hard-to … Web23 Sep 2024 · Thrombospondin-4 Is a Soluble Dermal Inflammatory Signal That Selectively Promotes Fibroblast Migration and Keratinocyte Proliferation for Skin Regeneration and Wound Healing Front Cell Dev Biol. 2024 Sep 23;9:745637. doi: … Web7 Jan 2024 · The splenic red pulp is composed of abundant fibroblasts that form the splenic cords and sinuses ( 1, 18 ). Perivascular cells that express stem cell antigen-1 (Sca-1) and platelet-derived growth factor receptor α and β (CD140a/b) line the venous sinuses and spleen arterioles, including pericytes and adventitial cells. corporate governance 2023